Registry News and Reports

Annual Cancer Incidence and Mortality Report

This annual report presents information on all new cancer cases and deaths occurring in the Greater Bay Area from 1988 to the latest year for which information is available. For more information, please visit our Annual Report webpage.


Recent trends in breast cancer incidence and mortality in Marin County

As part of our regular surveillance of cancer in the nine-county Greater Bay Area region, the Greater Bay Area Cancer Registry has carefully assessed recent trends in breast cancer incidence in the population of Marin County, a population for whom elevated rates had been reported among non-Hispanic whites in the past. Our review of the most complete incidence data (1988-2012) and mortality data (1988-2013) is available here.


Recent findings regarding elevated incidence of melanoma in Marin County

As part of our regular surveillance of cancer in the nine-county Greater Bay Area region of Callifornia, we have identified some recent changes in invasive melanoma incidence in the non-Hispanic white population of Marin County with implications for melanoma screening and prevention activities. Melanoma is now the second most commonly diagnosed cancer after prostate cancer for men in Marin County. Melanoma incidence in Marin County is 43% higher than the rest of the San Francisco Bay Area. Death rates from melanoma in Marin County are 18% higher than the California state average. CPIC and Marin County Health and Human Services issued a press release about the findings on July 23, 2014.

Please see the full report, Melanoma Incidence in Marin County, California, 1988 - 2011, for details of the findings, recommendations and next steps. 

Detailed studies regarding breast cancer in Marin County

The Greater Bay Area Cancer Registry closely monitors breast cancer rates in Marin County and the rest of the San Francisco Bay Area, where elevated rates have raised public concern in the past. Breast cancer incidence rates in Marin County increased dramatically in the last half of the 1990’s, peaked in 1999, and leveled off at a high rate between 1999 and 2003.
Breast cancer incidence then declined sharply for the years 2003 and 2004 both in the Bay Area and nationally.  Since 2004, incidence rates seem to have leveled off.  It is thought that these patterns track largely to prescription trends for menopausal hormone therapies, used by women for menopausal symptoms.

In July 2002, large numbers of women stopped taking hormone therapy after the announcement by the Women's Health Initiative that estrogen/progestin hormone therapy increases the risk of developing breast cancer and heart disease.  Reassuringly, breast cancer mortality rates have been declining consistently in Marin county, the Bay Area, California, and nationally.   We are continuing our collaboration with the Marin County Health Department and their long-term Marin Women's Study to better characterize patterns in hormone therapy use and breast cancer occurrence for Marin County.   

Our most recent review of breast cancer incidence and mortality for Marin has been summarized in the Recent trends in breast cancer incidence and mortality in Marin County, California, 1988-2012, An Update from the Greater Bay Area Cancer Registry, September 21, 2015. 

Please see the current Annual Cancer Incidence and Mortality Review for the latest statistics on the rates of in situ and invasive breast cancer for Marin and other counties in the Bay Area. Scientific articles that may be of interest are listed below.

When possible, links to the full text or abstract are provided; some publications require a subscription or fee to access more than the abstract online.

Ereman R, Prebil LA, Mockus M, Koblick K, Orenstein F, Benz C, Clarke CA. Recent trends in hormone therapy utilization and breast cancer incidence rates in the high incidence population of Marin County, California. BMC Public Health 2010; 10(1):228.

Robbins AS, Clarke CA. A decline in breast-cancer incidence. N Engl J Med 2007 Aug 2;357(5):511-2; author reply 513.

Clarke CA, Glaser SL. Declines in breast cancer after the WHI: apparent impact of hormone therapy. Cancer Causes Control 2007 Oct;18(8):847-52. Epub 2007 Jul 6. 

Robbins AS, Clarke CA. Regional changes in hormone therapy use and breast cancer incidence in California from 2001 to 2004. J Clin Oncol 2007 Aug 10;25(23):3437-9. Epub 2007 Jun 25. 

Clarke CA, Glaser SL, Uratsu CS, Selby JV, Kushi LH, Herrinton LJ. Recent declines in hormone therapy utilization and breast cancer incidence: clinical and population-based evidence. J Clin Oncol 2006 Nov 20;49-50.

Clarke CA, Purdie DM, Glaser SL. Population attributable risk of breast cancer in white women associated with immediately modifiable risk factors. BMC Cancer 2006 Jun 27;6:170. 

Update on breast cancer incidence patterns in Marin County and the San Francisco Bay Area, California. Northern California Cancer Center, September 2004. 

Clarke C, Glaser S, West D, et al. Breast cancer incidence and mortality trends in an affluent population: Marin County, California, USA, 1990-1999. Breast Cancer Res 2002; 4:R13.

Prehn A, Clarke C, Topol B, Glaser S, West D. Increase in breast cancer incidence in middle aged women during the 1990s. Ann Epidemiol 2002; 12:476-81. 

Prehn AW, West DW. Evaluating local differences in breast cancer incidence rates: a census based methodology (United States). Cancer Causes Control 1998; 9:511-7.

© Cancer Prevention Institute of California