Early-life Factors in Breast Cancer: Hormone Levels in Young Girls

Principal Investigator:
Esther M. John, Ph.D.
Julia Knight, Ph.D. (Mount Sinai Hospital, New York), Mary Jane De Souza, Ph.D. (Pennsylvania State University)
Funding Source:
Stanford Cancer Institute
Funding Period:
In adult women, hormones play an important role in the development of breast cancer. However, little is known about the role of hormones in pre-adolescent and adolescent girls. This pilot study will test the feasibility of collecting multiple urine samples over several months from 40 girls aged 10-13 years and of measuring urinary hormone levels, and will explore the relation between hormones and growth and pubertal development. The data obtained will be critical for the planning of a larger study within the LEGACY Girls Study.

© Cancer Prevention Institute of California