Imaging and Blood Biomarkers in Benign and Malignant Breast Disease
Ingrid Oakley-Girvan, Ph.D.
Sharon Pitteri, Ph.D., and Jafi Lipson, M.D. (Stanford University)
Breast cancer markers that could be tested in blood have not yet been discovered despite ongoing efforts to discover new molecular markers of disease. This study will evaluate two possible molecular markers in blood: leukocyte telomere length and circulating telomerase from women with breast cancer and benign tumors. This data will then be used with results of imaging to understand whether together, they improve upon the specificity and predictive value of either test when used independently. This study may help distinguish women with benign versus malignant breast cancers in new ways not requiring surgery and holds promise for developing new methods to catch breast cancer early.